Retina Research
-
- 术前玻璃体内贝伐单抗治疗增生性糖尿病视网膜病变继发的牵引性视网膜脱离
- Intravitreal Bevacizumab for Proliferative Diabetic Retinopathy
- Intravitreal Bevacizumab for Diabetic Macular Edema: 5-year Results
- 玻璃体内贝伐单抗治疗渗出性年龄相关性黄斑变性:5年结果
- 近视前后房人工晶状体植入术后的视网膜并发症
- Retinal Detachment in Down Syndrome: Characteristics and Surgical Outcomes
- 玻璃体部切除术治疗慢性创伤性黄斑裂孔的疗效观察
- Clinical Characteristics and Treatment of Panuveitis
- Retinal Detachment in Uveitis
-
Neil M. Bressler, M.D., graduated from the Johns Hopkins University School of Medicine, 在哈佛医学院马萨诸塞州眼耳医院完成了眼科住院医师, 并于1988年加入约翰霍普金斯大学医学院视网膜部(Wilmer眼科研究所-眼科)担任助理教授.
- He was promoted to Associate Professor in 1989, and then Professor in 1997, receiving the inaugural James P. Gills Professorship of Ophthalmology in 2000.
- He was Retina Division Chief 从2005年到2018年,并继续他的国际视网膜转诊实践至今.
- Since 2013, he has been Editor in Chief of JAMA Ophthalmology.
- Bressler has authored over 485 peer-reviewed publications, with academic pursuits including clinical trial and AI research in retina.
- He has Chaired multiple NIH-sponsored multicenter clinical trials, 包括20世纪90年代美国国立卫生研究院资助的黄斑下手术试验,以及2006年至2012年美国国立卫生研究院资助的DRCR视网膜网络.
- His commitments to service within the U.S. Department of Health and Human Services include 担任国家眼科研究所(NEI)内部临床试验数据和安全监测委员会主席 for over 20 years, since 2004.
- He also has participated on the 自2000年以来,FDA眼科器械小组24年,主持2008-2011年和2019-2024年.
- He was President of the Macula Society in 2013 and 2014.
- He is Program Director 约翰霍普金斯大学三届年度继续医学教育会议, currently with thousands of registrants each year.
- He also serves on the Board of Directors of the JAEB Center for Health Research Foundation, Inc. and the JAEB Center Research Trust, Inc., a freestanding, 多中心临床试验和流行病学研究的非营利性协调中心.
-
- All active protocols for the DRCR.net (Diabetes Clinical Research Network) including:
- 雷尼单抗+提示或延迟激光与曲安奈德+提示激光与局灶/干燥激光治疗糖尿病性黄斑水肿的比较
- 评估多种不同谱域OCT仪器的可重复性,并与糖尿病患者的时域OCT进行比较
- 雷尼单抗/贝伐单抗/阿非利塞普治疗糖尿病性黄斑水肿的比较
- 观察、激光与抗vegf治疗糖尿病性黄斑水肿视力良好的评价
- All active protocols for the DRCR.net (Diabetes Clinical Research Network) including:
-
-
- 用纳米药物给药——将药物直接输送到视网膜,可以持续长达6个月
- 确定糖尿病视网膜病变和AMD进展的机制以及可能导致进展的分子
- 识别视网膜疾病的保护因素,使保护因素得以增强
-
-
- Incontinentia pigmenti: Dr. 戈德堡正在重新评估他20年前最初研究的患者,以确定这种通常严重疾病的自然病程和适当治疗方法, 这种疾病只会遗传给女性,并会导致严重的视网膜(和大脑)关闭以及动脉和静脉过度生长, including major hemorrhages in the eye and brain.
-
- 研究氧化应激如何放大免疫反应以及视网膜如何保护自己
- How oxidized lipids damage the retina
- Designing cell therapy to treat myopia
- Creating new drugs to treat Stargardt's disease
- Using robotic surgery to improve retina surgery and to improve surgery education
-
-
- 了解早期糖尿病视网膜病变视网膜神经元改变的分子机制
- 糖尿病视网膜病变视网膜神经元与血管相互作用的研究
- 发现治疗/预防糖尿病视网膜病变的新分子靶点和途径
- Identifying biomarkers to diagnose early diabetic retinal disease
- 糖尿病前期和早期视网膜结构和功能改变的定义
-
- Epidemiology on health disparities in eye care
- Sickle cell anemia
- Age-related macular degeneration
- Retinal vein occlusion
-
- HIF(缺氧诱导因子)调节和失调在眼部疾病中的作用, 以确定治疗各种视力威胁疾病的新治疗方法为目标:
- Identification of a novel “bad” HIF target gene that promotes macular edema
- 检查“好”HIF靶基因在干性AMD中保护视网膜的作用
- 利用HIF靶基因靶向和破坏眼部新生血管疾病的病理血管.
- HIF(缺氧诱导因子)调节和失调在眼部疾病中的作用, 以确定治疗各种视力威胁疾病的新治疗方法为目标:
-
Dr. Solomon的研究旨在更好地了解特发性黄斑孔形成的病理生理学,并潜在地开发针对这种致盲疾病的靶向非手术治疗. The current treatment for idiopathic macular holes, which occur more commonly in women, involves surgery very often with prolonged face-down positioning. While successful, 手术可能伴随着严重的并发症,如白内障的形成, increased eye pressure, retinal tears, and retinal detachment.
因为在手术过程中会在眼睛内放置一个气泡来关闭黄斑孔, 手术后患者的视力会下降数天,由于需要长时间的面朝下的定位,患者失去了工作时间.
Dr. 所罗门的工作是实施蛋白质组学分析,以了解黄斑孔形成的发病机制. If successful, this research may elucidate the pathophysiology of other surgical retinal diseases, such as vitreomacular traction, lamellar holes, and epiretinal membranes, 所有这些都会导致阅读视力下降,需要手术干预.
Dr. 所罗门对黄斑孔的初步研究获得了全国的关注,并正在进行临床试验,将涉及全国各地的医疗中心.
-